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Scientists have uncovered antibodies that target the "dark side" of the flu virus. Influenza viruses have a mushroom-shaped protein known as neuraminidase (NA) that is said to have a "dark side" because the structure beneath its mushroom cap has been largely unexplored by science. Antibodies that latch onto this dark side could help form the basis for antiviral drugs and vaccines that work against many flu viruses, researchers wrote in a paper published Friday (March 1) in the journal Immunity . Currently, flu vaccines are designed to target a different structure on the surface of flu viruses: hemagglutinin (HA). This lollipop-shaped protein lets the viruses latch onto the outside of human cells and then infiltrate them. But it mutates rapidly, which is why the flu shot must be updated every year to match the HAs of circulating flu strains. Related: Never-before-seen antibodies can target many flu viruses By comparison, the dark side of NA doesn't mutate...

Jadon Sancho's return to Borussia Dortmund on loan this January rather sums up Manchester United's recent transfer business. The Red Devils have lacked a defined strategy in the market, often signing talented players with no cohesive plan on how to utilise their qualities once they arrive at Old Trafford. This has not only had a negative impact on the pitch, but also on the club's bank balance. As a result, not only will Man Utd have to look to offload a number of players next summer , but they will also have to be savvy in the transfer market. Looking at the pool of free agents currently floating around Europe's elite leagues may be one solution, especially when it comes to beefing up the periphery of the squad. Here are five free agents Erik ten Hag could target in the 2024 summer transfer window. Adrien Rabiot Rabiot has been linked with Man Utd in the past / Nicolò Campo/GettyImages A man that has come close to joining Man Utd in the past, Adrien Rabiot may once a...

Sandro Tonali's arrival at Newcastle United last summer was the beginning of a new era for the club. The £55m midfielder was a marquee signing for the Magpies and exemplified their ambitions having just qualified for the Champions League at the end of last campaign. The Italian made a fast start to life on Tyneside, but now faces an extremely uncertain future at St James' Park. Tonali is facing a lengthy ban after admitting to placing bets on matches involving his former club AC Milan, potentially resulting in a suspension from football of three years. While the midfielder's ban is likely to be reduced due to his cooperation with the Italian FA, his compatriot Nicolo Fagioli has already received a seven-month suspension for similar offences. Given that Tonali could feasibly miss the rest of Newcastle's campaign, or at least the majority of it, Eddie Howe may need to dip into the transfer market to replace his flagship signing. The 23-year-old's absence would leave ...